The Integrated Microscopy and Microanalytical Facility

Department of Chemistry, C. Emerson Bldg. Emory University
1515 Dickey Dr. Atlanta, GA 30322


PUBLICATIONS   


2006         2005       2004       2003        2002        2001        2000        1999        1998        1997        1996         1995       1994


2007

Lu K, Guo L, Mehta AK, Childers WS, Dublin SN, Skanthakumar S, Conticello VP, Thiyagarajan P, Apkarian RP and Lynn DG. Macroscale assembly of peptide nanotubes. Chem. Commun., 2007, 2729 - 2731

Keyes JW , Palmer AG, Erbil WK, Taylor JV, Apkarian RP ,Weeks ER and Lynn DG. Semagenesis and the parasitic angiosperm Striga asiatica. Plant J. 2007 Jun 15

Otsuka Y, Chronos NA, Apkarian RP, Robinson KA. Scanning electron microscopic analysis of defects in polymer coatings of three commercially available stents: comparison of BiodivYsio, Taxus and Cypher stents. J Invasive Cardiol. 2007 19 (2) 71-6

Syed Asad Ali Rizvi, Jie Zheng, Robert P. Apkarian, Steven N. Dublin, Shahab A. Shamsi. Polymeric Sulfated Amino Acid Surfactants: A Class of Versatile Chiral Selectors for Micellar Electrokinetic Chromatography (MEKC) and MEKC-MS. Anal. Chem. 2007, 79 (3) 879 - 898

Jordan SW, Haller CA, Sallach RE, Apkarian RP, Hanson SR, Chaikof EL. The effect of a recombinant elastin-mimetic coating of an ePTFE prosthesis on acute thrombogenicity in a baboon arteriovenous shunt. Biomaterials 2007, 28 (6) 1191-7

2006

Schlicher R, Radhakrishna H, Tolentino T., Apkarian R, Zarnitsyn V, Prausnitz M. Mechanism of intracellular delivery by acoustic cavitation. Ultrasound in Medicine & Biology 2006,32(6), 915-924

Jordan SW, Faucher KM, Caves JM, Apkarian RP, Rele SS, Sun XL, Hanson SR, Chaikof EL. Fabrication of a phospholipid membrane-mimetic film on the luminal surface of an ePTFE vascular graft Biomaterials 2006, (27) 18 3473-81.

Zimenkov Y, Dublin SN, Ni R, Tu RS, Breedveld V, Apkarian RP, Conticello VP.. Rational Design of a Reversible pH-Responsive Switch for Peptide Self-Assembly J Am Chem Soc. 2006, (128) 21 6770-6771.

Sung Y, Fletcher KE, Ritalahti KM, Apkarian RP, Ramos-Hernandez N, Sanford RA, Mesbah NM, Loffler FE. Geobacter lovleyi sp. nov. strain SZ, a novel metal-reducing and tetrachloroethene-dechlorinating bacterium. Appl Environ Microbiol. 2006, (72) 4 2775-82.

Sung Y, Ritalahti KM, Apkarian RP, Loffler FE. Quantitative PCR confirms purity of strain GT, a novel trichloroethene-to-ethene-respiring Dehalococcoides isolate. Appl Environ Microbiol. 2006, (72) 3 1980-7.

Jaeger DA, Mendoza A, Apkarian RP. Shamrock surfactants with terminal carboxylate headgroups and a central phosphorodithioate or quaternary ammonium headgroup. Langmuir 2006,(14) 22 1555-6021

2005

Jaeger DA, Mendoza A, Bragdon J, Arulsamy N, Li Z, Apkarian R.P. Surfactant quaternary ammonium hydrotris(1-pyrazolyl)borates Langmuir. 2005, 21 (21) 9440-5

Kai T., Sun Z.L., Faucher K.M., Apkarian R.P., Chaikof E.L., Design and synthesis of asymetricacyclic phospholipids bolaamphiphiles, Journal of Organic Chemistry, 2005, 70, 2606-2615.

Dohnalkova A., Marshall M.J., Kennedy D.W., Gorby Y.A., Shi L., Beliaev A., Apkarian R.P., Fredrickson J.M., The role of bacterial exopolymers in metal sorption and reduction, Microsc & Microanal., 2005, 11, 116-117.

Dong J., Apkarian R.P., Lynn D.G., Imaging Amyloid B peptide oligomeric particles in solution, Bioorganic and Medicinal Chemistry, 2005, 13, 5213-5217.

Sun H., Apkarian R.P., Dublin S.N., Tanaka K.A., Scanning Electron Microscopical Observations of Two Novel Hemostatic Polymers ,Journal of Thrombosis and Haemostasis, July 2005, 3, 1-2.

Apkarian, R.P., Wright E.R., Cryo and Cryo-Etch Methods For Quality Preservation of Hydrogels Imaged at High Magnification By Low Temperature SEM, 63rd Ann. Proc. Microsc. America. Microsc & Microanal. 2005 Supp.3 (In Press)

Apkarian, R.P. On The Rapid Cryoimmobilization Of Bulk Specimens For "Quality" Macromolecular Imaging By Low Temperature High Resolution SEM, 63rd Ann. Proc. Microsc. America. Microsc & Microanal. 2005 Supp.3 (In Press)

Nagapudi K., Brinkman W.T., Leisen J., Thomas B.S., Wright E.R., Haller C., Wu X., Apkarian R.P., Conticello, V.P., Chaikof, E.L. Protein-Based Thermoplastic Elastomers, Macromolecules; 2005;38, 345-354.

2004

Jaeger, D.A., Zeng, X., Apkarian, R.P. Shamrock surfactants: Synthesis and Characterization Langmuir 2004, 20, 10427-10432.

Castejon, O., Castellano, A., Arismendhi, G., Apkarian, R.P., Correlative microscopy of Purkinje dendritic spines. A field emission scanning and transmission electron microscopic study J.Submicrosc. Cytol. Pathol., 36 (1) 2004 .

Galloway, A.L., Menger, F.M., Apkarian, R.P. Cryoetch-HRSEM of Novel Ester Modified Surfactants. 62nd Ann. Proc. Microsc. America. Microsc & Microanal. 2004 (supp 2) 430-431CD.

Apkarian, R.P., Tanaka, K.Platelet activation by ADP and TRAP using cryo-HRSEM 62nd Ann. Proc. Microsc. America. Microsc & Microanal. 2004 (supp 2) 1224-1225CD.

Okun, N.M., Ritorto, M.D., Anderson, T.M., Apkarian, R.P., Hill, C.L. Polyoxometalates on Cationic Silica nanoparticles. Physiochemical properties of an electrstatically bound multi-iron catalyst. Chem. Mater 2004 16:2551-2558.

Menger, F.M., Galloway, A.L., Chebowski, M.E., Apkarian, R.P. Ultrastructure in frozenætched saline solutions: On the internal cleansing of ice. JACS 2004 126:5987-5989.

Dong, C.M., Sun, X.L.,Faucher, K.M., Apkarian, R.P., Chaikof E.L. Synthesis and characterization of glycopolymer-polypeptide triblock copolymers Biomacromolecules 2004 5:1 224-231.

Apkarian, R.P., Curtis, J.C., Sgoutas, D.S., Robinson, K.A. Effects of hypercholesterolemia on the adrenal cortex: potential role of adrenocortical dysfunction in atherogenesis. J.Cellular Physiol.(in preperation).

2003

Apkarian, R.P., Wright, E.R., Seredyuk, V.A. Eustis, S., Lyon, L.A., Conticello, V.P., Menger, F.M.   In-lens cryo-high resolution scanning electron microscopy: methodologies for molecular imaging of self-assembled organic hydrogels. Microsc. Microanal. 2003 9:4 286-295.

Wright, E.R., Conticello, V.P., Apkarian, R.P. Morphological characterization of elastin-mimetic block copolymers utilizing cryo- and cryoetch-HRSEM. Microsc. and Microanal. 2003 9:3, 171-182. Cover Image above.

Rubin, M.A., Jasiuk, I., Taylor, J.,Rubin, J., Ganey, T., Apkarian, R.P. TEM analysis of the Nanostructure of normal and osteoperotic human trabecular bone. Bone 2003 33:270-282.

Wright, E.R., Conticello, V.P., Apkarian, R.P. Cryo, Cryo-etch and tandem vryo-HRSEM correlated with cryo-STEM of elastin-mimetic block copolymers. 61st Ann. Proc. Microsc. Soc. America. Microsc. & Microanal. 2003 9(Suppl 2 254-255).

Apkarian, R.P., Wright, E.R., Seredyuk, V.A. Eustis, S., Lyon, L.A., Conticello, V.P., Menger, F.M. In-lens cryo-high resolution scanning electron microscopy: methodologies for molecular imaging of self-assembled organic hydrogels. 61st Ann. Proc. Microsc. Soc. America. Microsc. & Microanal. 2003 9(Suppl 2 1542-1543).

2002


Keyes, W.J., Lynn, D.G., Erbil, W.K., Taylor, J.V., and Apkarian, R.P. H2O2 in interspecies signaling: a new role in host detection. 60th Ann. Proc. Microsc. Soc. America. . Microsc. and Microanal. 8:suppl. 2 2002 962-63CD.2002 MSA Presidential Student Award.

Apkarian, R.P. TEM analysis of b-Amyloid fibrillogenesis: new strategy old problem. 60th Ann. Proc. Microsc. Soc. America. . Microsc. and Microanal. 8:Suppl.2, 2002 830-31CD.

Castejon, O.J., Dailey, M., Apkarian, R.P., Castejon, H.V. Correlative microscopy of cerebellar Bergmann Glial Cells. 60th Ann. Proc. Microsc. Soc. America. . Microsc. and Microanal. 8: Suppl. 2 2002 1032-1033CD.

Menger, F.M., Seredyuk, V.A., Apkarian, R.P., Wright, E.R. Colloidal assemblies of branched geminis studied by cryo-etch-HRSEM. J. Am. Chem. Soc. 2002: 12408-12409.

Morgan, D.M., Dong, J., Lu, K., Apkarian, R.P., Lynn, D.G. Metal switch for amyloid formation: Insight into the structure of the nucleus. J. Am. Chem. Soc. 2002:12644-45.

Nagapudi, K., Brinkman, W.T., Leisen, J.E., Huang,L., McMillan,R.A., Apkarian, R.P., Conticello, V.P., Chaikof, E.L. Photomediated Solid-State Cross-Linking of an Elastin-Mimetic Recombinant Protein Polymer, Macromolecules; 2002;35, 1730-1737.

Hongbo, L., Faucher, K.M., Sun, X-L., Feng, J., Johnson, T.L., Orban, J.M., Apkarian, R.P., Dluhy, R.A., Chaikof ,E.L. A membrane-mimetic barrier for cell encapsulation. Langmuir; 2002 18,1332-1339.

Wright, E.R., McMillan, R.A., Cooper, A., Apkarian, R.P., Conticello, V.P. Thermoplastic elastomer hydrogels via self-assembly of an elastin-mimetic triblock polypeptide. Adv. Funct. Mater. 2002 12:2, 149-154.

Menger, F.M. Zhang H., Caran, K.L., Seredyuk V., Apkarian, R.P. Gemini-Induced columnar jointing in vitreous ice. Cryo-HRSEM as a tool for discovering new colloidal morphologies. J. Am. Chem. Soc. 2002 124:7 1140-1141.

2001


Keyes, W.J., Taylor, J.V., Apkarian, R.P., Lynn, D.G. Dancing together: Social controls in parasitic plant development. Plant physiol. 2001 127: 1508-1512.

Apkarian, R.P. Mixing tandem cryo-HRSEM and cryo-STEM images of cells and macromolecular assemblies. 59th Ann. Proc. Microsc. Soc. America. 2001: 722-723.

Wright, E.R., Conticello, V.P., Apkarian, R.P. Morphological characterization of an elastin-mimetic triblock copolymer utilizing cryo-HRSEM. 59th Ann. Proc. Microsc. Soc. America. 2001:136-137.

Castejon, O.J., Castejon, H.V., Apkarian, R.P. Confocal scanning laser microscopy, scanning and transmission electron microscopy of vertebrate cerebellar granule cells. 59th Ann. Proc. Microsc.Soc. America. 2001:662-663.

Huang, L., Apkarian, R.P., Chaikof, E.L. High resolution analysis of engineered typeI collegen nanofibers by electron microscopy. Scanning 2001::372-375.

Huang, L., Nagapudi, K., Apkarian, R.P. Chaikof, E.L. Engineered collagen-PEO nanofibers and fabrics. J. of Biomater. Sci., Polymer Ed. 2001 12:9 979-993.

Castejon, O.J., Castejon,H.V., Apkarian, R.P. Confocal laserscanningand scanning and transmission electron microscopy of vertebrate cerebellar granule cells. Cell and Mol. Biol. 2001.

2000


Apkarian, R.P. Correlative studies employing high Resolution SEM, STEM, and TEM in ambient and Cryo-modes for molecular imaging in the biomedical sciences. Acta Microscopica. No.1-2000:20-25.

Menger, F.M., Peresypkin, A.V., Caran, K.L., Apkarian, R.P. A sponge morphology in an elementary coacervate. Langmuir 2000: 16; 9113-9116.

Castejon, O.J., Apkarian, R.P., Castejon, H.V. Field emission scanning electron microscopy of mouse cerebellar synaptic contacts. 58th Ann. Proc.Microsc. Soc. America. 2000: 844-845.

Apkarian, R.P., Lee, T.A.T., Conticello, R.P. Metal coating techniques for contrast enhancement of biological macromolecular complexes in HRSEM, STEM, and TEM image modes. 58th Ann. Proc. Microsc. Soc. America. 2000: 292- 293.

Lee, T.A.T., Cooper, A., Apkarian, R.P., Conticello, V.P. Thermo-reversible self-assembly of nanoparticles derived from elastin-mimetic polypeptides. Adv. Mater. 2000 12:15; 1105-1110.

Qu, Y., Payne, S.C., Apkarian, R.P., and Conticello, V.P. Self-assembly of polypeptide multi-block copolymer modeled on arachnid dragline silk proteins. J. Am. Chem. Soc. 2000 (5014-5015).

Huang, L., McMillan, R.A., Apkarian, R.P., Pourdeyhimi,B., Conticello, V.P., and Chaikof, E.L. Generation of synthetic elastin-mimetic small diameter fibers and fiber networks. Macromolecules 2000 33: 2989-2997.

Menger, F.M., Caran, K.L., Apkarian, R.P., In-lens cryo-high-resolution scanning electron microscopy of large vesicles. Langmuir. 2000: 16, 98-101.

1999


Apkarian, R.P., Caran, K.L., Robinson, K.A. Topographic imaging of chromium-coated frozen-hydrated cell and macromolecular complexes by in-lens field emission Scanning Electron Microscopy. Microsc. and Microanal. 1999 5:3 197- 207.

McMillan, R.A., Caran, K.L., Apkarian, R.P., Conticello, V.P. High resolution topographic imaging of environmentally responsive elastin-mimetic hydrogels under native conditions: evidence for structural rearrangements during the phase transition. Macromolecules. 1999: 32, 9067-9070.

Wendt, M..C., Robinson, K.A., Chronos, N.A.F., Caran, K.L., Apkarian, R.P. Application of cryo-high resolution (HR) SEM technique for imaging platelet morphology. 57th Ann. Proc. Microsc. Soc. America. 1999: 1116-1117.

Caran, K.L., Apkarian, R.P., Menger, F.M. Examination of large unilamellar vesicles (LUVs) using cryo-HRSEM and cryo- STEM. 57th Ann. Proc. Microsc. Soc. America. 1999: 1210-1211.

McMillan, R.A., Apkarian, R.P., Conticello, V.P. Elastin-mimetic covalently crosslinked synthetic protein networks: Solvent and temperature dependent morphological features imaged by SEM. 57th Ann. Proc. Microsc. Soc. America. 1999: 396-397.

Childs, S., Hagen, K., Apkarian, R. Fabricationof organic supramolecular micro-structures: Pre-organization, epitaxial surface recognition and controlled growth in a model system of biomineralization. 57th Ann. Proc. Microsc. Soc. America. 1999: 382-383.58.

Karr, J.F., Apkarian, R.P., Petros, J.A. Cationic peptide mediated oligonucleotide delivery to DU145 prostate cancer cells - Cell surface binding detected by high resolution SEM. 57th Ann. Proc. Microsc. Soc. America. 1999: 392-393.

1998


Apkarian, R.P., Lee,S., Keiper, J. Refining equipment for high-resolution in-lens cryo-SEM. 56th Ann. Proc. Microsc. Soc. America. 1998; 258-259.

Apkarian, R.P. In-lens cryo scanning electron microscopy of biological specimens. Proc. 14th International Congress on Electron Microscopy. 1998; 4:279-280.


1997


Marijianowski, M.M.H. Cipolla, G.D. Forestner, D.M. Campbell, P.K. Weselcouch, E.O. Slepian, M.J. Apkarian, R.P. Histologic consequences of endoluminal coronary artery hydrogel polymer paving. 55th Ann. Proc. Microsc. Soc. America. 1997; 315-316.

Apkarian, R.P. Lund, S. Imaging cultured cells on protein coated silicon chips using low-voltage in-lens SEM. 55th Ann. Proc. Microsc. Soc. America.1997; 1229-1230.

Apkarian, R. P The Fine Structure of Fenestrated Adenocortical Capillaries Revealed by In-Lens Field Emission Scanning Electron Microscopy and Scanning Transmission Electron Microscopy, Scanning, Vol. 19, 361-367, 1997.

1996


Apkarian, R.P., Lee, S., Menger, F.M. An Improved Method for Preparation and Stereo Imaging of Negatively Stained Phospholipid Vesicles by Field-Emission STEM. 54th Ann. Proc. Microsc. Soc. America; 914-915, 1996.

Apkarian, R.P. An In-lens Cryostage for Secondary Electron-I and Scanning Transmission Microscopy. 54th Ann. Proc. Microsc. Soc. America; 816-817,
1996.

1995


Apkarian, R.P. Tarr, J.A. Kaufman, M.J. and Menger, F.M. High magnification in-lens field emission SE-I SEM of carbon based styrenes, diamonds and endothelial cell membranes. 53rd Ann. Proc. Microsc. Soc. America; 860-861, 1995.

1994


Apkarian, R.P. Analysis of High Quality Monatomic Films Used in Biological High Resolution Scanning Electron Microscopy Scanning Microsc.8:2, 289-301, 1994.

Beckers, A.L., de Bruijn WC., Jongkind J.F., Cleton-Soeteman M.I., Apkarian R.P., Gelsema E.S. Energy-filtering transmission electron microscopy as a tool for structural and compositional analysis of isolated ferritin particles. Scanning Microsc. 8:suppl. 261-275, 1994.

Apkarian, R.P. Dual-stage choreography of bulk biological specimens by Schottky field-emission SEM: Quality imaging at all magnifications. 52nd Ann. Proc. Microsc. Soc. America; 1014-1015, 1994.

Castejon, O.J., Apkarian, R.P., Valero, C. Conventional and high resolution scanning electron microscopy and cryofracture techniques as tools for tracing cerebellar short intracortical circuits. Scanning Microsc. 8:2, 315-324, 1994.

Castejon, O.J., Castejon,H.V., Apkarian, R.P. Proteoglycan ultracytochemistry and conventional and high resolution scanning electron microscopy of vertebrate cerebellar parallel fiber presynaptic endings. Cell. and Mol. Biol.40:6,795-801, 1994.

Castejon, O.J., Castejon, H.V., Apkarian, R.P. High resolution (SE-I) scanning electron microscopy features of primate cerebellar cortex. Cell and Mol. Biol. 40:8 1173-1181, 1994.